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Immunotherapy resistance in Triple-negative breast cancer (TNBC)

PROJECTS_

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Differential IFN-α response and immunotherapy resistance in triple-negative breast cancer

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Therapeutic reversion of immune evasion of triple-negative breast cancer stem cells

Celià-Terrassa Lab

The Celià-Terrassa’s Lab started in January 2018 and focuses on understanding the complexity and dynamics of metastasis, in particular the molecular mechanisms regulating breast cancer stem cells (bCSCs) and their interplay with the metastatic niche. We are interested on studying the molecular mechanisms underlying Cancer Stem Cell (CSC) cellular plasticity leading tumor progression, chemorresistance and relapse, as a major challenge to efficiently target breast cancer metastasis.