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New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

Celià-Terrassa Lab

The Celià-Terrassa’s Lab started in January 2018 and focuses on understanding the complexity and dynamics of metastasis, in particular the molecular mechanisms regulating breast cancer stem cells (bCSCs) and their interplay with the metastatic niche. We are interested on studying the molecular mechanisms underlying Cancer Stem Cell (CSC) cellular plasticity leading tumor progression, chemorresistance and relapse, as a major challenge to efficiently target breast cancer metastasis.